Migren ve epizodik gerilim tipi baş ağrılarının hematolojik parametreler ile ilişkisi































































ABSTRACT
Demirel H., The Association between Haematological Parameters, Migraine and Episodic Tension Type Headache, Zonguldak Karaelmas University Faculty of Medicine, Thesis of Neurology. Zonguldak, 2007
Migraine and tension type headache (TTH) are the most common primary headaches, which affect the activities of daily living. Although the relationship between haematological diseases (anemia, polycytemia, heamochromatosis) and headache is accepted in neurology practice, studies examining iron deficiency or metabolism in patients with episodic tension type headache (ETTH) and migraine are in limited number. In this study we aimed to investigate the relationship between primary headaches (migraine and episodic tension type headache) and iron deficiency anemia. 132 migraine and 120 ETTH patients, diagnosed and followed-up at Neurology and Headache out-patient clinics of Zonguldak Karaelmas University, Faculty of Medicine, between December 2005 and July 2007 were included into study. For diagnosis International Headache Society (IHS) diagnostic criteria for headache disorders (2004) was used. Total blood count examinations, serum iron, Iron Binding Capacity (IBC), ferritin, platelet (Plt), vitamin B12 and folic acid levels were examined in all patients. All data were analyzed with the statistical package for the social sciences (SPSS) version 11.0 for Windows. Independent students t-test, Mann-Whitney U test, spearman rank correlation and pearson chi-square tests were used.The level of significance was chosen to be P < 0.05. In migraine group, the increased frequency of headache was correlated with elevated level of ferritin (r=0,187, p=0,032), and decreased level of IBC (r=-0,184, p=0,035). There was no correlation between the frequency of headache and other parameters (hemoglobin (Hb), Hematocrit (Htc), serum iron and Plt levels).In TTH patients, the increased frequency of headache was found to be correlated with decreased levels of Hb (r=-0,252, p=0,005), Htc (r=-0,208, p=0,023), ferritin (r=-0,260, p=0,004), and increased level of IBC (r=0,214, p=0,019). There was no correlation between the frequency of headache and serum iron, and Plt levels. In all patients, no correlation was found between the haematological parameters and duration and severity of headache. In conclusion, this study emphasizes that in patients with primary headaches, especially TTH, examination of iron metabolism will be helpful in planning the treatment. Keywords: Migraine, episodic tension type headache, iron deficiency anemia. 5



5. SAYFAYA BENZER SAYFALAR

Gerilim tipi başağrısı olan hastalarla fibromiyalji sendromlu hastaların ve kontrol grubunun serum total oksidan, antioksidan ve nitrik oksit düzeylerinin karşılaştırılması - Sayfa 8
V IV. ABSTRACT COMPARISON OF LEVEL OF PLASMA TOTAL OXIDANT/ANTIOXIDANT AND NITRIC OXIDE BETWEEN TENSION TYPE HEADACHE, FIBROMYALGIA SYNDROME AND CONTROL GROUP Dr. M. Fatih YİMENİCİOĞLU Residency Thesis, Department of Neurology Supervisor: Assoc. Prof. Dr. A. Münife NEYAL December 2008, 62 pages Tension-type headache (TTH) and fibromyalgia syndrome (FMS) are chronic pain syndromes. Both diseas...
Multipl sklerozda baş ağrısı - Sayfa 68
headache types seen during relapses as tension type headache, remaining 9.1% of them described migraine in that period. All MS patients who had migraine begun after the beginning of MS and had headache during relapses described their headache types seen during relapses as migraine; there was correlation between headache type begun after the onset of the disease and also seen during relapses (p:0.0...
Migren ve gerilim tipi başağrısında vitamin B6, vitamin B12 ve folik asit eksikliğinin önemi - Sayfa 176
different in migraine (p=0.005 and p=0.014 respectively) and in tension type headache groups (p= 0.013 and p=0.006 respectively) than the control group. When the patients with migraine were assessed separately as migraine without aura and with aura, vitamin B6 and MMA levels were significantly different between migraine without aura and control groups (p=0.012 and p=0.015 respectively) however in ...

5. SAYFADAKI ANAHTAR KELIMELER

with
headache
type
that
between
migraine


5. SAYFA ICERIGI

ABSTRACT
Demirel H., The Association between Haematological Parameters, Migraine and Episodic Tension Type Headache, Zonguldak Karaelmas University Faculty of Medicine, Thesis of Neurology. Zonguldak, 2007
Migraine and tension type headache (TTH) are the most common primary headaches, which affect the activities of daily living. Although the relationship between haematological diseases (anemia, polycytemia, heamochromatosis) and headache is accepted in neurology practice, studies examining iron deficiency or metabolism in patients with episodic tension type headache (ETTH) and migraine are in limited number. In this study we aimed to investigate the relationship between primary headaches (migraine and episodic tension type headache) and iron deficiency anemia. 132 migraine and 120 ETTH patients, diagnosed and followed-up at Neurology and Headache out-patient clinics of Zonguldak Karaelmas University, Faculty of Medicine, between December 2005 and July 2007 were included into study. For diagnosis International Headache Society (IHS) diagnostic criteria for headache disorders (2004) was used. Total blood count examinations, serum iron, Iron Binding Capacity (IBC), ferritin, platelet (Plt), vitamin B12 and folic acid levels were examined in all patients. All data were analyzed with the statistical package for the social sciences (SPSS) version 11.0 for Windows. Independent students t-test, Mann-Whitney U test, spearman rank correlation and pearson chi-square tests were used.The level of significance was chosen to be P < 0.05. In migraine group, the increased frequency of headache was correlated with elevated level of ferritin (r=0,187, p=0,032), and decreased level of IBC (r=-0,184, p=0,035). There was no correlation between the frequency of headache and other parameters (hemoglobin (Hb), Hematocrit (Htc), serum iron and Plt levels).In TTH patients, the increased frequency of headache was found to be correlated with decreased levels of Hb (r=-0,252, p=0,005), Htc (r=-0,208, p=0,023), ferritin (r=-0,260, p=0,004), and increased level of IBC (r=0,214, p=0,019). There was no correlation between the frequency of headache and serum iron, and Plt levels. In all patients, no correlation was found between the haematological parameters and duration and severity of headache. In conclusion, this study emphasizes that in patients with primary headaches, especially TTH, examination of iron metabolism will be helpful in planning the treatment. Keywords: Migraine, episodic tension type headache, iron deficiency anemia. 5

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